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Prototype Prescribing Outlier Dashboard for NHS Cheshire CCG

At OpenPrescribing we are piloting a number of data-driven approaches to identify unusual prescribing and collect feedback on this prescribing to inform development of new tools to support prescribers and organisations to audit and review prescribing. These pilot results are provided for the interest of advanced users, although we don't know how relevant they are in practice. There is substantial variation in prescribing behaviours, across various different areas of medicine. Some variation can be explained by demographic changes, or local policies or guidelines, but much of the remaining variation is less easy to explain.

The DataLab is keen to hear your feedback on the results. You can do this by completing the following survey or emailing us at [email protected]. Please DO NOT INCLUDE IDENTIFIABLE PATIENT information in your feedback. All feedback is helpful, you can send short or detailed feedback.

This report has been developed to automatically identify prescribing patterns at a chemical level which are furthest away from “typical prescribing” and can be classified as an “outlier”. We calculate the number of prescriptions for each chemical in the BNF coding system, the count of all prescriptions within that chemical's BNF subparagraph, for prescriptions dispensed between June 2021 and December 2021. We then calculate the ratio of these counts along with the mean and standard deviation of those ratios across all CCGs. From this we can calculate the “z-score”, which is a measure of how many standard deviations a given CCG is from the population mean. We then rank your “z-scores” to find the top 10 results where prescribing is an outlier for prescribing higher than its peers and those where it is an outlier for prescribing lower than its peers.

For each outlier chemical, a kernel density estimation plot of all CCG's chemical:subparagraph ratios is provided, with this CCG's ratio overlaid in red.

It is important to remember that this information was generated automatically and it is therefore likely that some of the behaviour is warranted. This report seeks only to collect information about where this variation may be warranted and where it might not, to inform research on this topic. Our full analytical method code is openly available on GitHub here.

This is a new, experimental feature. We'd love to .

Prescribing where NHS Cheshire CCG is higher than most

BNF Chemical Chemical Items BNF Subparagraph Subparagraph Items Ratio Mean std Z_Score Plots
Chloroprocaine hydrochloride 1 Local anaesthetics 9,223 0.00 0.00 0.00 10.20
Mannitol 6 Mucolytics 22,733 0.00 0.00 0.00 9.38
Fluorescein sodium 23 Ocular diagnostic & peri-operative prepn & photodynamic tt 424 0.05 0.01 0.01 4.36
Gluten free pastas 2 Foods for special diets 8,737 0.00 0.00 0.00 4.09
Calcitriol 1,828 Vitamin D 217,461 0.01 0.00 0.00 3.82
Amphotericin 3 Polyene antifungals 3,850 0.00 0.00 0.00 3.81
Flutamide 26 Prostate cancer and gonadorelin analogues 6,783 0.00 0.00 0.00 3.65
Urine testing reagents 2,692 Diabetic diagnostic and monitoring agents 51,715 0.05 0.01 0.01 3.61
Gluten free/wheat free cereals 1 Foods for special diets 8,737 0.00 0.00 0.00 3.48
Quinidine sulfate 7 Drugs for arrhythmias 8,121 0.00 0.00 0.00 3.18

Prescribing where NHS Cheshire CCG is lower than most

BNF Chemical Chemical Items BNF Subparagraph Subparagraph Items Ratio Mean std Z_Score Plots
Nystatin 3,847 Polyene antifungals 3,850 1.00 1.00 0.00 -3.81
Co-cyprindiol (Cyprote acetate/ethinylestradiol) 460 Oral preparations for acne 830 0.55 0.94 0.14 -2.71
Oral rehydration salts 1,149 Oral sodium and water 2,772 0.41 0.65 0.11 -2.04
Sodium chloride 660 Topical nasal decongestants 2,089 0.32 0.56 0.13 -1.87
Aripiprazole 7,292 Antipsychotic drugs 84,170 0.09 0.12 0.02 -1.64
Glucose blood testing reagents 46,826 Diabetic diagnostic and monitoring agents 51,715 0.91 0.94 0.02 -1.62
Gentamicin sulfate 2 Aminoglycosides 13 0.15 0.68 0.35 -1.48
Furosemide 83,707 Loop diuretics 108,423 0.77 0.86 0.06 -1.44
Calcium acetate 257 Phosphate binding agents 1,512 0.17 0.47 0.21 -1.43
Peppermint oil 2,996 Antispasmodic and other drugs altering gut motility 41,046 0.07 0.11 0.03 -1.39