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Prototype Prescribing Outlier Dashboard for NHS North Cumbria CCG

At OpenPrescribing we are piloting a number of data-driven approaches to identify unusual prescribing and collect feedback on this prescribing to inform development of new tools to support prescribers and organisations to audit and review prescribing. These pilot results are provided for the interest of advanced users, although we don't know how relevant they are in practice. There is substantial variation in prescribing behaviours, across various different areas of medicine. Some variation can be explained by demographic changes, or local policies or guidelines, but much of the remaining variation is less easy to explain.

The DataLab is keen to hear your feedback on the results. You can do this by completing the following survey or emailing us at [email protected]. Please DO NOT INCLUDE IDENTIFIABLE PATIENT information in your feedback. All feedback is helpful, you can send short or detailed feedback.

This report has been developed to automatically identify prescribing patterns at a chemical level which are furthest away from “typical prescribing” and can be classified as an “outlier”. We calculate the number of prescriptions for each chemical in the BNF coding system, the count of all prescriptions within that chemical's BNF subparagraph, for prescriptions dispensed between June 2021 and December 2021. We then calculate the ratio of these counts along with the mean and standard deviation of those ratios across all CCGs. From this we can calculate the “z-score”, which is a measure of how many standard deviations a given CCG is from the population mean. We then rank your “z-scores” to find the top 10 results where prescribing is an outlier for prescribing higher than its peers and those where it is an outlier for prescribing lower than its peers.

For each outlier chemical, a kernel density estimation plot of all CCG's chemical:subparagraph ratios is provided, with this CCG's ratio overlaid in red.

It is important to remember that this information was generated automatically and it is therefore likely that some of the behaviour is warranted. This report seeks only to collect information about where this variation may be warranted and where it might not, to inform research on this topic. Our full analytical method code is openly available on GitHub here.

This is a new, experimental feature. We'd love to .

Prescribing where NHS North Cumbria CCG is higher than most

BNF Chemical Chemical Items BNF Subparagraph Subparagraph Items Ratio Mean std Z_Score Plots
Meningococcal C vaccine 1 Vaccines and antisera 75,050 0.00 0.00 0.00 10.20
Procarbazine hydrochloride 1 Other antineoplastic drugs 309 0.00 0.00 0.00 9.52
Dronabinol/cannabidiol 110 Skeletal muscle relaxants 8,001 0.01 0.00 0.00 6.92
Deferiprone 5 Hypoplastic/haemolytic and renal anaemias 25 0.20 0.01 0.03 5.52
Indoramin 689 Drugs for urinary retention 38,763 0.02 0.00 0.00 5.45
Other magnesium preparations 67 Magnesium 861 0.08 0.01 0.01 4.99
Nystatin 5 Vaginal and vulval infections 2,858 0.00 0.00 0.00 4.91
Erdosteine 298 Mucolytics 10,535 0.03 0.00 0.01 4.55
Pridinol mesilate 60 Skeletal muscle relaxants 8,001 0.01 0.00 0.00 4.30
Sodium benzoate 8 Drugs used in metabolic disorders 8 1.00 0.09 0.21 4.29

Prescribing where NHS North Cumbria CCG is lower than most

BNF Chemical Chemical Items BNF Subparagraph Subparagraph Items Ratio Mean std Z_Score Plots
Sodium picosulfate 22 Bowel cleansing preparations 205 0.11 0.73 0.19 -3.30
Atropine sulfate 159 Mydriatics and cycloplegics 347 0.46 0.74 0.10 -2.86
Co-cyprindiol (Cyprote acetate/ethinylestradiol) 203 Oral preparations for acne 353 0.58 0.94 0.14 -2.56
Co-amilofruse (Amiloride hydrochloride/frusemide) 170 Potassium sparing diuretics and compounds 356 0.48 0.72 0.10 -2.33
Gamolenic acid 8 Preparations for eczema 19 0.42 0.90 0.21 -2.28
Senna 10,730 Stimulant laxatives 31,959 0.34 0.55 0.10 -2.27
Crotamiton 208 Topical local anaesthetics and antipruritics 1,373 0.15 0.34 0.09 -2.00
Tiotropium bromide 6,223 Antimuscarinic bronchodilators 14,305 0.44 0.70 0.14 -1.89
Indapamide 13,983 Thiazides and related diuretics 53,726 0.26 0.40 0.08 -1.83
Hydrocortisone 1,401 Use of corticosteroids 35,482 0.04 0.07 0.01 -1.82