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Prototype Prescribing Outlier Dashboard for NHS Oxfordshire CCG

At OpenPrescribing we are piloting a number of data-driven approaches to identify unusual prescribing and collect feedback on this prescribing to inform development of new tools to support prescribers and organisations to audit and review prescribing. These pilot results are provided for the interest of advanced users, although we don't know how relevant they are in practice. There is substantial variation in prescribing behaviours, across various different areas of medicine. Some variation can be explained by demographic changes, or local policies or guidelines, but much of the remaining variation is less easy to explain.

The DataLab is keen to hear your feedback on the results. You can do this by completing the following survey or emailing us at [email protected]. Please DO NOT INCLUDE IDENTIFIABLE PATIENT information in your feedback. All feedback is helpful, you can send short or detailed feedback.

This report has been developed to automatically identify prescribing patterns at a chemical level which are furthest away from “typical prescribing” and can be classified as an “outlier”. We calculate the number of prescriptions for each chemical in the BNF coding system, the count of all prescriptions within that chemical's BNF subparagraph, for prescriptions dispensed between June 2021 and December 2021. We then calculate the ratio of these counts along with the mean and standard deviation of those ratios across all CCGs. From this we can calculate the “z-score”, which is a measure of how many standard deviations a given CCG is from the population mean. We then rank your “z-scores” to find the top 10 results where prescribing is an outlier for prescribing higher than its peers and those where it is an outlier for prescribing lower than its peers.

For each outlier chemical, a kernel density estimation plot of all CCG's chemical:subparagraph ratios is provided, with this CCG's ratio overlaid in red.

It is important to remember that this information was generated automatically and it is therefore likely that some of the behaviour is warranted. This report seeks only to collect information about where this variation may be warranted and where it might not, to inform research on this topic. Our full analytical method code is openly available on GitHub here.

This is a new, experimental feature. We'd love to .

Prescribing where NHS Oxfordshire CCG is higher than most

BNF Chemical Chemical Items BNF Subparagraph Subparagraph Items Ratio Mean std Z_Score Plots
Dequalinium chloride 1 Lozenges and sprays 16 0.06 0.00 0.01 9.95
Clozapine 664 Antipsychotic drugs 61,966 0.01 0.00 0.00 9.33
Macitentan 1 Vasodilator antihypertensive drugs 472 0.00 0.00 0.00 9.01
Norethisterone enantate 4 Parenteral progestogen-only contraceptives 5,771 0.00 0.00 0.00 7.98
Alprazolam 1 Anxiolytics 27,074 0.00 0.00 0.00 6.64
Olsalazine sodium 320 Aminosalicylates 12,613 0.03 0.00 0.00 4.88
Gluten free/wheat free grains/flours 45 Foods for special diets 8,269 0.01 0.00 0.00 4.36
Bupropion hydrochloride 374 Nicotine dependence 555 0.67 0.14 0.12 4.36
Eprosartan 1,824 Angiotensin-II receptor antagonists 160,771 0.01 0.00 0.00 4.18
Denosumab 4,283 Bisphosphonates and other drugs 63,537 0.07 0.01 0.01 4.03

Prescribing where NHS Oxfordshire CCG is lower than most

BNF Chemical Chemical Items BNF Subparagraph Subparagraph Items Ratio Mean std Z_Score Plots
Solifenacin 5,139 Drugs for urinary frequency enuresis and incontinence 48,040 0.11 0.33 0.06 -3.54
Calcipotriol 5,512 Preparations for psoriasis 7,123 0.77 0.87 0.03 -3.36
Doxycycline hyclate 14,753 Tetracyclines 26,924 0.55 0.71 0.06 -2.69
Betahistine hydrochloride 5,421 Drugs used in nausea and vertigo 34,293 0.16 0.28 0.05 -2.29
Rifaximin 81 Some other antibacterials 2,441 0.03 0.45 0.19 -2.20
Sodium chloride 346 Topical nasal decongestants 1,240 0.28 0.56 0.13 -2.15
Nicotine 171 Nicotine dependence 555 0.31 0.71 0.19 -2.11
Prednisolone 35,692 Use of corticosteroids 41,633 0.86 0.89 0.02 -2.08
Benzoyl peroxide and clindamycin phosphate 2,934 Topical preparations for acne 11,021 0.27 0.37 0.05 -2.00
Brinzolamide 3,226 Treatment of glaucoma 62,936 0.05 0.10 0.02 -1.97