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Prototype Prescribing Outlier Dashboard for NHS Kirklees CCG

At OpenPrescribing we are piloting a number of data-driven approaches to identify unusual prescribing and collect feedback on this prescribing to inform development of new tools to support prescribers and organisations to audit and review prescribing. These pilot results are provided for the interest of advanced users, although we don't know how relevant they are in practice. There is substantial variation in prescribing behaviours, across various different areas of medicine. Some variation can be explained by demographic changes, or local policies or guidelines, but much of the remaining variation is less easy to explain.

The DataLab is keen to hear your feedback on the results. You can do this by completing the following survey or emailing us at [email protected]. Please DO NOT INCLUDE IDENTIFIABLE PATIENT information in your feedback. All feedback is helpful, you can send short or detailed feedback.

This report has been developed to automatically identify prescribing patterns at a chemical level which are furthest away from “typical prescribing” and can be classified as an “outlier”. We calculate the number of prescriptions for each chemical in the BNF coding system, the count of all prescriptions within that chemical's BNF subparagraph, for prescriptions dispensed between June 2021 and December 2021. We then calculate the ratio of these counts along with the mean and standard deviation of those ratios across all CCGs. From this we can calculate the “z-score”, which is a measure of how many standard deviations a given CCG is from the population mean. We then rank your “z-scores” to find the top 10 results where prescribing is an outlier for prescribing higher than its peers and those where it is an outlier for prescribing lower than its peers.

For each outlier chemical, a kernel density estimation plot of all CCG's chemical:subparagraph ratios is provided, with this CCG's ratio overlaid in red.

It is important to remember that this information was generated automatically and it is therefore likely that some of the behaviour is warranted. This report seeks only to collect information about where this variation may be warranted and where it might not, to inform research on this topic. Our full analytical method code is openly available on GitHub here.

This is a new, experimental feature. We'd love to .

Prescribing where NHS Kirklees CCG is higher than most

BNF Chemical Chemical Items BNF Subparagraph Subparagraph Items Ratio Mean std Z_Score Plots
Caffeine 33 CNS Stimulants and drugs used for ADHD 3,877 0.01 0.0 0.0 10.14
Ergotamine tartrate 7 Treatment of acute migraine 10,964 0.00 0.0 0.0 10.02
Hydrocortisone acetate 4 Corticosteroids 267 0.01 0.0 0.0 7.46
Disodium edetate 2 Ocular diagnostic & peri-operative prepn & photodynamic tt 239 0.01 0.0 0.0 6.80
Saxagliptin/dapagliflozin 823 Other antidiabetic drugs 74,157 0.01 0.0 0.0 6.59
Undecenoates 70 Antifungal preparations 5,605 0.01 0.0 0.0 5.60
Other antiviral preparations 2 Antiviral preparations 485 0.00 0.0 0.0 5.20
Trimipramine maleate 462 Tricyclic and related antidepressant drugs 84,657 0.01 0.0 0.0 5.07
Olsalazine sodium 257 Aminosalicylates 10,222 0.03 0.0 0.0 4.83
Distigmine bromide 3 Drugs for urinary retention 38,322 0.00 0.0 0.0 4.63

Prescribing where NHS Kirklees CCG is lower than most

BNF Chemical Chemical Items BNF Subparagraph Subparagraph Items Ratio Mean std Z_Score Plots
Sodium cromoglicate 13 Cromoglycate and related therapy 15 0.87 0.99 0.03 -3.88
Other amino acidandnutritional agent preparations 64 Amino acids and nutritional agents 138 0.46 0.95 0.14 -3.44
Medroxyprogesterone acetate 5 Progestogens 105 0.05 0.67 0.25 -2.43
Potassium citrate 56 Drugs used in urological pain 70 0.80 0.94 0.06 -2.42
Aciclovir 482 Antiviral preparations 485 0.99 1.00 0.00 -2.24
Cyclopentolate hydrochloride 13 Mydriatics and cycloplegics 261 0.05 0.24 0.10 -1.96
Cefalexin 2,170 Cephalosporins 2,488 0.87 0.96 0.05 -1.79
Flecainide acetate 998 Drugs for arrhythmias 3,497 0.29 0.48 0.11 -1.79
Chlorhexidine gluconate 697 Mouth-washes, gargles and dentifrices 740 0.94 0.98 0.02 -1.76
Emollient bath and shower preparations 3,629 Emollient bath and shower preparations 7,675 0.47 0.64 0.09 -1.75