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Prototype Prescribing Outlier Dashboard for Horizon PCN

At OpenPrescribing we are piloting a number of data-driven approaches to identify unusual prescribing and collect feedback on this prescribing to inform development of new tools to support prescribers and organisations to audit and review prescribing. These pilot results are provided for the interest of advanced users, although we don't know how relevant they are in practice. There is substantial variation in prescribing behaviours, across various different areas of medicine. Some variation can be explained by demographic changes, or local policies or guidelines, but much of the remaining variation is less easy to explain.

The DataLab is keen to hear your feedback on the results. You can do this by completing the following survey or emailing us at [email protected]. Please DO NOT INCLUDE IDENTIFIABLE PATIENT information in your feedback. All feedback is helpful, you can send short or detailed feedback.

This report has been developed to automatically identify prescribing patterns at a chemical level which are furthest away from “typical prescribing” and can be classified as an “outlier”. We calculate the number of prescriptions for each chemical in the BNF coding system, the count of all prescriptions within that chemical's BNF subparagraph, for prescriptions dispensed between June 2021 and December 2021. We then calculate the ratio of these counts along with the mean and standard deviation of those ratios across all PCNs. From this we can calculate the “z-score”, which is a measure of how many standard deviations a given PCN is from the population mean. We then rank your “z-scores” to find the top 10 results where prescribing is an outlier for prescribing higher than its peers and those where it is an outlier for prescribing lower than its peers.

For each outlier chemical, a kernel density estimation plot of all PCN's chemical:subparagraph ratios is provided, with this PCN's ratio overlaid in red.

It is important to remember that this information was generated automatically and it is therefore likely that some of the behaviour is warranted. This report seeks only to collect information about where this variation may be warranted and where it might not, to inform research on this topic. Our full analytical method code is openly available on GitHub here.

This is a new, experimental feature. We'd love to .

Prescribing where Horizon PCN is higher than most

BNF Chemical Chemical Items BNF Subparagraph Subparagraph Items Ratio Mean std Z_Score Plots
Fondaparinux sodium 23 Parenteral anticoagulants 132 0.17 0.01 0.02 8.37
Chloroquine phosphate 4 Antimalarials 385 0.01 0.00 0.00 5.18
Other oral iron preparations 100 Oral iron 5,332 0.02 0.00 0.00 5.10
Promazine hydrochloride 1,204 Antipsychotic drugs 7,851 0.15 0.01 0.03 4.49
Etodolac 441 Non-steroidal anti-inflammatory drugs 7,927 0.06 0.01 0.01 4.22
Erythromycin stearate 42 Macrolides 2,276 0.02 0.00 0.00 4.18
Probenecid 7 Gout and cytotoxic induced hyperiuicaemia 4,701 0.00 0.00 0.00 3.67
Benperidol 31 Antipsychotic drugs 7,851 0.00 0.00 0.00 3.41
Fluticasone propionate/azelastine hydrochloride (Nasal) 1,028 Drugs used in nasal allergy 4,974 0.21 0.06 0.04 3.39
Fidaxomicin 2 Some other antibacterials 77 0.03 0.00 0.01 3.35

Prescribing where Horizon PCN is lower than most

BNF Chemical Chemical Items BNF Subparagraph Subparagraph Items Ratio Mean std Z_Score Plots
Gliclazide 2,226 Sulfonylureas 3,564 0.62 0.93 0.11 -2.74
Quinine sulfate 277 Antimalarials 385 0.72 0.90 0.08 -2.34
Folic acid 3,346 Drugs used in megaloblastic anaemias 8,635 0.39 0.68 0.13 -2.19
Methotrexate 833 Rheumatic disease suppressant drugs 2,332 0.36 0.58 0.11 -2.07
Glucose blood testing reagents 4,255 Diabetic diagnostic and monitoring agents 4,732 0.90 0.94 0.02 -1.82
Diclofenac sodium 16 Sunscreening preparations 258 0.06 0.36 0.18 -1.68
Mometasone furoate 788 Drugs used in nasal allergy 4,974 0.16 0.32 0.10 -1.67
Metoclopramide hydrochloride 231 Drugs used in nausea and vertigo 4,950 0.05 0.12 0.04 -1.66
Loperamide hydrochloride 1,232 Antimotility drugs 1,245 0.99 1.00 0.00 -1.64
Linagliptin 436 Other antidiabetic drugs 10,558 0.04 0.16 0.07 -1.64