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Prototype Prescribing Outlier Dashboard for Sale Central PCN

At OpenPrescribing we are piloting a number of data-driven approaches to identify unusual prescribing and collect feedback on this prescribing to inform development of new tools to support prescribers and organisations to audit and review prescribing. These pilot results are provided for the interest of advanced users, although we don't know how relevant they are in practice. There is substantial variation in prescribing behaviours, across various different areas of medicine. Some variation can be explained by demographic changes, or local policies or guidelines, but much of the remaining variation is less easy to explain.

The DataLab is keen to hear your feedback on the results. You can do this by completing the following survey or emailing us at [email protected]. Please DO NOT INCLUDE IDENTIFIABLE PATIENT information in your feedback. All feedback is helpful, you can send short or detailed feedback.

This report has been developed to automatically identify prescribing patterns at a chemical level which are furthest away from “typical prescribing” and can be classified as an “outlier”. We calculate the number of prescriptions for each chemical in the BNF coding system, the count of all prescriptions within that chemical's BNF subparagraph, for prescriptions dispensed between June 2021 and December 2021. We then calculate the ratio of these counts along with the mean and standard deviation of those ratios across all PCNs. From this we can calculate the “z-score”, which is a measure of how many standard deviations a given PCN is from the population mean. We then rank your “z-scores” to find the top 10 results where prescribing is an outlier for prescribing higher than its peers and those where it is an outlier for prescribing lower than its peers.

For each outlier chemical, a kernel density estimation plot of all PCN's chemical:subparagraph ratios is provided, with this PCN's ratio overlaid in red.

It is important to remember that this information was generated automatically and it is therefore likely that some of the behaviour is warranted. This report seeks only to collect information about where this variation may be warranted and where it might not, to inform research on this topic. Our full analytical method code is openly available on GitHub here.

This is a new, experimental feature. We'd love to .

Prescribing where Sale Central PCN is higher than most

BNF Chemical Chemical Items BNF Subparagraph Subparagraph Items Ratio Mean std Z_Score Plots
Benperidol 46 Antipsychotic drugs 6,962 0.01 0.00 0.00 5.90
Bupivacaine hydrochloride 102 Local anaesthetics 701 0.15 0.01 0.03 4.20
Irbesartan with diuretic 204 Angiotensin-II receptor antagonists 12,843 0.02 0.00 0.00 3.34
Chloroquine phosphate 7 Antimalarials 1,055 0.01 0.00 0.00 3.24
Nortriptyline 1,364 Tricyclic and related antidepressant drugs 12,054 0.11 0.04 0.02 3.03
Timolol 675 Treatment of glaucoma 5,457 0.12 0.06 0.02 3.00
Prednisolone acetate 228 Corticosteroids 511 0.45 0.14 0.11 2.75
Metformin hydrochloride/pioglitazone 72 Other antidiabetic drugs 9,537 0.01 0.00 0.00 2.67
Travoprost 546 Treatment of glaucoma 5,457 0.10 0.03 0.03 2.55
Terbutaline sulphate 597 Selective beta(2)-agonists 13,834 0.04 0.02 0.01 2.50

Prescribing where Sale Central PCN is lower than most

BNF Chemical Chemical Items BNF Subparagraph Subparagraph Items Ratio Mean std Z_Score Plots
Amitriptyline hydrochloride 8,215 Tricyclic and related antidepressant drugs 12,054 0.68 0.84 0.05 -2.99
Losartan potassium 2,061 Angiotensin-II receptor antagonists 12,843 0.16 0.50 0.16 -2.18
Timolol and bimatoprost 78 Treatment of glaucoma 5,457 0.01 0.10 0.04 -2.11
Spironolactone 1,445 Potassium-sparing diuretics and aldosterone antagonists 2,779 0.52 0.72 0.10 -2.08
Sodium picosulfate 0 Bowel cleansing preparations 3 0.00 0.70 0.35 -2.04
    Lidocaine hydrochloride 546 Local anaesthetics 701 0.78 0.91 0.07 -1.91
    Nicorandil 624 Other antianginal drugs 2,336 0.27 0.51 0.14 -1.74
    Donepezil hydrochloride 959 Drugs for dementia 3,135 0.31 0.48 0.11 -1.60
    Medroxyprogesterone acetate 0 Progestogens 1 0.00 0.65 0.41 -1.59
      Amiodarone hydrochloride 119 Drugs for arrhythmias 479 0.25 0.48 0.15 -1.52