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Prototype Prescribing Outlier Dashboard for Colne Valley PCN

At OpenPrescribing we are piloting a number of data-driven approaches to identify unusual prescribing and collect feedback on this prescribing to inform development of new tools to support prescribers and organisations to audit and review prescribing. These pilot results are provided for the interest of advanced users, although we don't know how relevant they are in practice. There is substantial variation in prescribing behaviours, across various different areas of medicine. Some variation can be explained by demographic changes, or local policies or guidelines, but much of the remaining variation is less easy to explain.

The DataLab is keen to hear your feedback on the results. You can do this by completing the following survey or emailing us at [email protected]. Please DO NOT INCLUDE IDENTIFIABLE PATIENT information in your feedback. All feedback is helpful, you can send short or detailed feedback.

This report has been developed to automatically identify prescribing patterns at a chemical level which are furthest away from “typical prescribing” and can be classified as an “outlier”. We calculate the number of prescriptions for each chemical in the BNF coding system, the count of all prescriptions within that chemical's BNF subparagraph, for prescriptions dispensed between June 2021 and December 2021. We then calculate the ratio of these counts along with the mean and standard deviation of those ratios across all PCNs. From this we can calculate the “z-score”, which is a measure of how many standard deviations a given PCN is from the population mean. We then rank your “z-scores” to find the top 10 results where prescribing is an outlier for prescribing higher than its peers and those where it is an outlier for prescribing lower than its peers.

For each outlier chemical, a kernel density estimation plot of all PCN's chemical:subparagraph ratios is provided, with this PCN's ratio overlaid in red.

It is important to remember that this information was generated automatically and it is therefore likely that some of the behaviour is warranted. This report seeks only to collect information about where this variation may be warranted and where it might not, to inform research on this topic. Our full analytical method code is openly available on GitHub here.

This is a new, experimental feature. We'd love to .

Prescribing where Colne Valley PCN is higher than most

BNF Chemical Chemical Items BNF Subparagraph Subparagraph Items Ratio Mean std Z_Score Plots
Ketamine hydrochloride 30 Drugs used in nausea and vertigo 3,957 0.01 0.00 0.00 9.22
Low protein grains/flours 11 Foods for special diets 518 0.02 0.00 0.00 5.60
Benzylpenicillin sodium (Penicillin G) 3 Benzylpenicillin and phenoxymethylpenicillin 1,380 0.00 0.00 0.00 5.39
Erdosteine 51 Mucolytics 1,562 0.03 0.00 0.01 4.80
Dapagliflozin/metformin 191 Other antidiabetic drugs 6,701 0.03 0.00 0.01 3.87
Galantamine 248 Drugs for dementia 1,357 0.18 0.03 0.04 3.69
Asenapine 10 Drugs used for mania and hypomania 925 0.01 0.00 0.00 3.69
Clindamycin phosphate 24 Vaginal and vulval infections 242 0.10 0.03 0.02 3.66
Mercaptamine 5 Drugs used in metabolic disorders 6 0.83 0.07 0.24 3.18
Hydrochlorothiazide 11 Thiazides and related diuretics 8,302 0.00 0.00 0.00 3.09

Prescribing where Colne Valley PCN is lower than most

BNF Chemical Chemical Items BNF Subparagraph Subparagraph Items Ratio Mean std Z_Score Plots
Phenoxymethylpenicillin (Penicillin V) 1,377 Benzylpenicillin and phenoxymethylpenicillin 1,380 1.00 1.00 0.00 -5.39
Clotrimazole 184 Vaginal and vulval infections 242 0.76 0.90 0.05 -2.91
Alcohol 0 Alcohols and saline 2 0.00 0.87 0.33 -2.62
    Hyoscine butylbromide 436 Antispasmodic and other drugs altering gut motility 2,379 0.18 0.33 0.06 -2.42
    Neomycin sulfate 143 Nasal preparations for infection 214 0.67 0.83 0.07 -2.39
    Sertraline hydrochloride 10,753 Selective serotonin re-uptake inhibitors 32,204 0.33 0.46 0.06 -2.25
    Menthol 7 Topical local anaesthetics and antipruritics 60 0.12 0.47 0.17 -1.99
    Amiodarone hydrochloride 157 Drugs for arrhythmias 821 0.19 0.48 0.15 -1.90
    Latanoprost 1,282 Treatment of glaucoma 6,631 0.19 0.31 0.07 -1.72
    Apixaban 2,925 Oral anticoagulants 14,131 0.21 0.41 0.12 -1.65