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Prototype Prescribing Outlier Dashboard for Modality (Keighley) PCN

At OpenPrescribing we are piloting a number of data-driven approaches to identify unusual prescribing and collect feedback on this prescribing to inform development of new tools to support prescribers and organisations to audit and review prescribing. These pilot results are provided for the interest of advanced users, although we don't know how relevant they are in practice. There is substantial variation in prescribing behaviours, across various different areas of medicine. Some variation can be explained by demographic changes, or local policies or guidelines, but much of the remaining variation is less easy to explain.

The DataLab is keen to hear your feedback on the results. You can do this by completing the following survey or emailing us at [email protected]. Please DO NOT INCLUDE IDENTIFIABLE PATIENT information in your feedback. All feedback is helpful, you can send short or detailed feedback.

This report has been developed to automatically identify prescribing patterns at a chemical level which are furthest away from “typical prescribing” and can be classified as an “outlier”. We calculate the number of prescriptions for each chemical in the BNF coding system, the count of all prescriptions within that chemical's BNF subparagraph, for prescriptions dispensed between June 2021 and December 2021. We then calculate the ratio of these counts along with the mean and standard deviation of those ratios across all PCNs. From this we can calculate the “z-score”, which is a measure of how many standard deviations a given PCN is from the population mean. We then rank your “z-scores” to find the top 10 results where prescribing is an outlier for prescribing higher than its peers and those where it is an outlier for prescribing lower than its peers.

For each outlier chemical, a kernel density estimation plot of all PCN's chemical:subparagraph ratios is provided, with this PCN's ratio overlaid in red.

It is important to remember that this information was generated automatically and it is therefore likely that some of the behaviour is warranted. This report seeks only to collect information about where this variation may be warranted and where it might not, to inform research on this topic. Our full analytical method code is openly available on GitHub here.

This is a new, experimental feature. We'd love to .

Prescribing where Modality (Keighley) PCN is higher than most

BNF Chemical Chemical Items BNF Subparagraph Subparagraph Items Ratio Mean std Z_Score Plots
Sulfur 7 Topical preparations for acne 1,195 0.01 0.00 0.00 15.94
Tacalcitol 155 Preparations for psoriasis 1,178 0.13 0.00 0.01 11.45
Nandrolone decanoate 1 Anabolic steroids 1 1.00 0.01 0.10 10.30
Dipipanone hydrochloride 65 Opioid analgesics 21,564 0.00 0.00 0.00 9.47
Isotretinoin 139 Oral preparations for acne 155 0.90 0.03 0.12 7.15
Patiromer calcium 17 Oral potassium 80 0.21 0.01 0.03 6.79
Freeze sprays and gels 10 Rubefacients, topical NSAIDS, capsaicin and poultice 7,013 0.00 0.00 0.00 6.77
Risedronate sodium 2,927 Bisphosphonates and other drugs 5,811 0.50 0.09 0.07 6.12
Glimepiride 4,509 Sulfonylureas 6,386 0.71 0.07 0.11 5.75
Sodium benzoate 13 Drugs used in metabolic disorders 14 0.93 0.09 0.27 3.16

Prescribing where Modality (Keighley) PCN is lower than most

BNF Chemical Chemical Items BNF Subparagraph Subparagraph Items Ratio Mean std Z_Score Plots
Co-cyprindiol (Cyprote acetate/ethinylestradiol) 16 Oral preparations for acne 155 0.10 0.97 0.12 -7.15
Prasterone 0 Anabolic steroids 1 0.00 0.97 0.15 -6.37
    Alendronic acid 2,329 Bisphosphonates and other drugs 5,811 0.40 0.87 0.07 -6.35
    Gliclazide 1,871 Sulfonylureas 6,386 0.29 0.93 0.11 -5.72
    Calcipotriol 815 Preparations for psoriasis 1,178 0.69 0.87 0.04 -4.14
    Prucalopride 34 Other drugs used in constipation 195 0.17 0.73 0.19 -3.02
    Potassium chloride 61 Oral potassium 80 0.76 0.97 0.07 -2.84
    Mebeverine hydrochloride 1,493 Antispasmodic and other drugs altering gut motility 4,793 0.31 0.45 0.07 -2.15
    Omeprazole 14,065 Proton pump inhibitors 71,395 0.20 0.51 0.15 -2.07
    Betamethasone valerate 1,960 Topical corticosteroids 10,290 0.19 0.28 0.04 -2.07