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Prototype Prescribing Outlier Dashboard for Humbleyard Practice

At OpenPrescribing we are piloting a number of data-driven approaches to identify unusual prescribing and collect feedback on this prescribing to inform development of new tools to support prescribers and organisations to audit and review prescribing. These pilot results are provided for the interest of advanced users, although we don't know how relevant they are in practice. There is substantial variation in prescribing behaviours, across various different areas of medicine. Some variation can be explained by demographic changes, or local policies or guidelines, but much of the remaining variation is less easy to explain.

The DataLab is keen to hear your feedback on the results. You can do this by completing the following survey or emailing us at [email protected]. Please DO NOT INCLUDE IDENTIFIABLE PATIENT information in your feedback. All feedback is helpful, you can send short or detailed feedback.

This report has been developed to automatically identify prescribing patterns at a chemical level which are furthest away from “typical prescribing” and can be classified as an “outlier”. We calculate the number of prescriptions for each chemical in the BNF coding system, the count of all prescriptions within that chemical's BNF subparagraph, for prescriptions dispensed between June 2021 and December 2021. We then calculate the ratio of these counts along with the mean and standard deviation of those ratios across all Practices. From this we can calculate the “z-score”, which is a measure of how many standard deviations a given Practice is from the population mean. We then rank your “z-scores” to find the top 10 results where prescribing is an outlier for prescribing higher than its peers and those where it is an outlier for prescribing lower than its peers.

For each outlier chemical, a kernel density estimation plot of all Practice's chemical:subparagraph ratios is provided, with this Practice's ratio overlaid in red.

It is important to remember that this information was generated automatically and it is therefore likely that some of the behaviour is warranted. This report seeks only to collect information about where this variation may be warranted and where it might not, to inform research on this topic. Our full analytical method code is openly available on GitHub here.

This is a new, experimental feature. We'd love to .

Prescribing where Humbleyard Practice is higher than most

BNF Chemical Chemical Items BNF Subparagraph Subparagraph Items Ratio Mean std Z_Score Plots
Pericyazine 306 Antipsychotic drugs 1,836 0.17 0.00 0.02 8.45
Meptazinol hydrochloride 317 Opioid analgesics 4,292 0.07 0.00 0.01 6.75
Co-danthramer (Dantron/poloxamer 188) 8 Stimulant laxatives 912 0.01 0.00 0.00 6.57
Perindopril erbumine 7,294 Angiotensin-converting enzyme inhibitors 11,906 0.61 0.09 0.10 5.37
Methadone hydrochloride 74 Opioid analgesics 4,292 0.02 0.00 0.00 4.36
Doxepin 64 Tricyclic and related antidepressant drugs 3,949 0.02 0.00 0.00 3.95
Primidone 173 Control of epilepsy 6,438 0.03 0.00 0.01 3.75
Magnesium lactate 4 Magnesium 19 0.21 0.01 0.06 3.49
Sotalol hydrochloride 368 Beta-adrenoceptor blocking drugs 9,143 0.04 0.01 0.01 3.12
Sodium fusidate 7 Some other antibacterials 36 0.19 0.01 0.06 2.87

Prescribing where Humbleyard Practice is lower than most

BNF Chemical Chemical Items BNF Subparagraph Subparagraph Items Ratio Mean std Z_Score Plots
Ramipril 3,057 Angiotensin-converting enzyme inhibitors 11,906 0.26 0.69 0.17 -2.64
Baclofen 211 Skeletal muscle relaxants 485 0.44 0.83 0.18 -2.16
Losartan potassium 613 Angiotensin-II receptor antagonists 5,477 0.11 0.50 0.19 -2.10
Levonorgestrel 0 Emergency contraception 3 0.00 0.61 0.31 -1.97
    Amlodipine 6,377 Calcium-channel blockers 11,914 0.54 0.76 0.11 -1.96
    Solifenacin 269 Drugs for urinary frequency enuresis and incontinence 1,800 0.15 0.33 0.11 -1.61
    Calcium carbonate 54 Calcium supplements 72 0.75 0.95 0.13 -1.53
    Tamsulosin hydrochloride 2,244 Drugs for urinary retention 2,692 0.83 0.92 0.06 -1.44
    Atorvastatin 10,208 Lipid-regulating drugs 18,397 0.55 0.67 0.08 -1.42
    Beclometasone dipropionate 2,069 Corticosteroids (respiratory) 4,958 0.42 0.58 0.12 -1.39