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Prototype Prescribing Outlier Dashboard for The New Medical Centre

At OpenPrescribing we are piloting a number of data-driven approaches to identify unusual prescribing and collect feedback on this prescribing to inform development of new tools to support prescribers and organisations to audit and review prescribing. These pilot results are provided for the interest of advanced users, although we don't know how relevant they are in practice. There is substantial variation in prescribing behaviours, across various different areas of medicine. Some variation can be explained by demographic changes, or local policies or guidelines, but much of the remaining variation is less easy to explain.

The DataLab is keen to hear your feedback on the results. You can do this by completing the following survey or emailing us at [email protected]. Please DO NOT INCLUDE IDENTIFIABLE PATIENT information in your feedback. All feedback is helpful, you can send short or detailed feedback.

This report has been developed to automatically identify prescribing patterns at a chemical level which are furthest away from “typical prescribing” and can be classified as an “outlier”. We calculate the number of prescriptions for each chemical in the BNF coding system, the count of all prescriptions within that chemical's BNF subparagraph, for prescriptions dispensed between June 2021 and December 2021. We then calculate the ratio of these counts along with the mean and standard deviation of those ratios across all Practices. From this we can calculate the “z-score”, which is a measure of how many standard deviations a given Practice is from the population mean. We then rank your “z-scores” to find the top 10 results where prescribing is an outlier for prescribing higher than its peers and those where it is an outlier for prescribing lower than its peers.

For each outlier chemical, a kernel density estimation plot of all Practice's chemical:subparagraph ratios is provided, with this Practice's ratio overlaid in red.

It is important to remember that this information was generated automatically and it is therefore likely that some of the behaviour is warranted. This report seeks only to collect information about where this variation may be warranted and where it might not, to inform research on this topic. Our full analytical method code is openly available on GitHub here.

This is a new, experimental feature. We'd love to .

Prescribing where The New Medical Centre is higher than most

BNF Chemical Chemical Items BNF Subparagraph Subparagraph Items Ratio Mean std Z_Score Plots
Ramipril with calcium channel blocker 33 Angiotensin-converting enzyme inhibitors 4,351 0.01 0.00 0.00 11.66
Econazole nitrate 26 Vaginal and vulval infections 96 0.27 0.01 0.03 9.81
Piroxicam 122 Rubefacients, topical NSAIDS, capsaicin and poultice 217 0.56 0.05 0.09 5.76
Mebeverine hydrochloride compound preparations 26 Antispasmodic and other drugs altering gut motility 262 0.10 0.01 0.02 4.49
Cefadroxil 1 Cephalosporins 29 0.03 0.00 0.01 4.03
Dexamethasone phosphate 11 Use of corticosteroids 697 0.02 0.00 0.00 3.97
Sodium clodronate 12 Bisphosphonates and other drugs 605 0.02 0.00 0.00 3.96
Fesoterodine fumarate 104 Drugs for urinary frequency enuresis and incontinence 618 0.17 0.03 0.04 3.90
Bromocriptine 5 Bromocriptine and other dopaminergic drugs 5 1.00 0.10 0.23 3.87
Isotretinoin 4 Oral preparations for acne 8 0.50 0.02 0.13 3.79

Prescribing where The New Medical Centre is lower than most

BNF Chemical Chemical Items BNF Subparagraph Subparagraph Items Ratio Mean std Z_Score Plots
Co-cyprindiol (Cyprote acetate/ethinylestradiol) 4 Oral preparations for acne 8 0.50 0.98 0.13 -3.79
Cabergoline 0 Bromocriptine and other dopaminergic drugs 5 0.00 0.86 0.27 -3.17
    Mercaptopurine 0 Antimetabolites 6 0.00 0.80 0.35 -2.32
      Clotrimazole 68 Vaginal and vulval infections 96 0.71 0.90 0.09 -2.26
      Levonorgestrel 0 Emergency contraception 1 0.00 0.61 0.31 -1.97
        Cetirizine hydrochloride 61 Antihistamines 760 0.08 0.28 0.11 -1.88
        Sertraline hydrochloride 1,107 Selective serotonin re-uptake inhibitors 3,754 0.29 0.46 0.09 -1.88
        Hypromellose 56 Tear deficiency, eye lubricant/astringent 340 0.16 0.45 0.15 -1.88
        Neomycin sulfate 25 Nasal preparations for infection 43 0.58 0.84 0.14 -1.86
        Oral rehydration salts 12 Oral sodium and water 71 0.17 0.71 0.29 -1.84