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Prototype Prescribing Outlier Dashboard for St. Agnes Surgery

At OpenPrescribing we are piloting a number of data-driven approaches to identify unusual prescribing and collect feedback on this prescribing to inform development of new tools to support prescribers and organisations to audit and review prescribing. These pilot results are provided for the interest of advanced users, although we don't know how relevant they are in practice. There is substantial variation in prescribing behaviours, across various different areas of medicine. Some variation can be explained by demographic changes, or local policies or guidelines, but much of the remaining variation is less easy to explain.

The DataLab is keen to hear your feedback on the results. You can do this by completing the following survey or emailing us at [email protected]. Please DO NOT INCLUDE IDENTIFIABLE PATIENT information in your feedback. All feedback is helpful, you can send short or detailed feedback.

This report has been developed to automatically identify prescribing patterns at a chemical level which are furthest away from “typical prescribing” and can be classified as an “outlier”. We calculate the number of prescriptions for each chemical in the BNF coding system, the count of all prescriptions within that chemical's BNF subparagraph, for prescriptions dispensed between June 2021 and December 2021. We then calculate the ratio of these counts along with the mean and standard deviation of those ratios across all Practices. From this we can calculate the “z-score”, which is a measure of how many standard deviations a given Practice is from the population mean. We then rank your “z-scores” to find the top 10 results where prescribing is an outlier for prescribing higher than its peers and those where it is an outlier for prescribing lower than its peers.

For each outlier chemical, a kernel density estimation plot of all Practice's chemical:subparagraph ratios is provided, with this Practice's ratio overlaid in red.

It is important to remember that this information was generated automatically and it is therefore likely that some of the behaviour is warranted. This report seeks only to collect information about where this variation may be warranted and where it might not, to inform research on this topic. Our full analytical method code is openly available on GitHub here.

This is a new, experimental feature. We'd love to .

Prescribing where St. Agnes Surgery is higher than most

BNF Chemical Chemical Items BNF Subparagraph Subparagraph Items Ratio Mean std Z_Score Plots
Trimetazidine hydrochloride 35 Calcium-channel blockers 3,595 0.01 0.00 0.00 68.39
Maltodextrin 9 Foods for special diets 29 0.31 0.01 0.02 13.77
Co-flumactone (Hydroflumethiazide/spironolactone) 8 Potassium sparing diuretics and compounds 33 0.24 0.00 0.02 13.45
Nalmefene 2 Alcohol dependence 3 0.67 0.01 0.08 7.84
Isotretinoin 2 Oral preparations for acne 2 1.00 0.02 0.13 7.77
Naphazoline hydrochloride 2 Other anti-inflammatory preparations 65 0.03 0.00 0.01 5.59
Hydromorphone hydrochloride 9 Opioid analgesics 1,337 0.01 0.00 0.00 5.49
Prazosin hydrochloride 31 Alpha-adrenoceptor blocking drugs 533 0.06 0.00 0.01 4.45
Trihexyphenidyl hydrochloride 13 Antimuscarinic drugs used in parkinsonism 13 1.00 0.15 0.20 4.18
Dexamethasone sodium metasulphobenzoate 41 Otitis externa 153 0.27 0.04 0.05 4.10

Prescribing where St. Agnes Surgery is lower than most

BNF Chemical Chemical Items BNF Subparagraph Subparagraph Items Ratio Mean std Z_Score Plots
Co-cyprindiol (Cyprote acetate/ethinylestradiol) 0 Oral preparations for acne 2 0.00 0.98 0.13 -7.77
    Procyclidine hydrochloride 0 Antimuscarinic drugs used in parkinsonism 13 0.00 0.85 0.21 -4.10
      Simple 1 Expectorant and demulcent cough preparations 2 0.50 0.96 0.17 -2.72
      Doxazosin mesilate 502 Alpha-adrenoceptor blocking drugs 533 0.94 0.99 0.02 -2.53
      Ramipril 1,347 Angiotensin-converting enzyme inhibitors 4,833 0.28 0.69 0.17 -2.51
      Other food for special diet preparations 3 Foods for special diets 29 0.10 0.65 0.24 -2.25
      Glycopyrronium bromide 1 Antimuscarinic drugs 21 0.05 0.82 0.35 -2.20
      Levothyroxine sodium 3,836 Thyroid hormones 3,863 0.99 1.00 0.00 -1.89
      Medroxyprogesterone acetate 9 Parenteral progestogen-only contraceptives 15 0.60 0.88 0.15 -1.84
      Dexamethasone 85 Otitis externa 153 0.56 0.78 0.12 -1.83