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Prototype Prescribing Outlier Dashboard for Castlefields

At OpenPrescribing we are piloting a number of data-driven approaches to identify unusual prescribing and collect feedback on this prescribing to inform development of new tools to support prescribers and organisations to audit and review prescribing. These pilot results are provided for the interest of advanced users, although we don't know how relevant they are in practice. There is substantial variation in prescribing behaviours, across various different areas of medicine. Some variation can be explained by demographic changes, or local policies or guidelines, but much of the remaining variation is less easy to explain.

The DataLab is keen to hear your feedback on the results. You can do this by completing the following survey or emailing us at [email protected]. Please DO NOT INCLUDE IDENTIFIABLE PATIENT information in your feedback. All feedback is helpful, you can send short or detailed feedback.

This report has been developed to automatically identify prescribing patterns at a chemical level which are furthest away from “typical prescribing” and can be classified as an “outlier”. We calculate the number of prescriptions for each chemical in the BNF coding system, the count of all prescriptions within that chemical's BNF subparagraph, for prescriptions dispensed between June 2021 and December 2021. We then calculate the ratio of these counts along with the mean and standard deviation of those ratios across all Practices. From this we can calculate the “z-score”, which is a measure of how many standard deviations a given Practice is from the population mean. We then rank your “z-scores” to find the top 10 results where prescribing is an outlier for prescribing higher than its peers and those where it is an outlier for prescribing lower than its peers.

For each outlier chemical, a kernel density estimation plot of all Practice's chemical:subparagraph ratios is provided, with this Practice's ratio overlaid in red.

It is important to remember that this information was generated automatically and it is therefore likely that some of the behaviour is warranted. This report seeks only to collect information about where this variation may be warranted and where it might not, to inform research on this topic. Our full analytical method code is openly available on GitHub here.

This is a new, experimental feature. We'd love to .

Prescribing where Castlefields is higher than most

BNF Chemical Chemical Items BNF Subparagraph Subparagraph Items Ratio Mean std Z_Score Plots
Fluvastatin sodium 102 Lipid-regulating drugs 4,717 0.02 0.00 0.00 10.39
Mepyramine maleate 1 Topical local anaesthetics and antipruritics 4 0.25 0.00 0.03 9.08
Guaifenesin 1 Expectorant and demulcent cough preparations 1 1.00 0.03 0.14 6.78
Low protein cakes 8 Foods for special diets 212 0.04 0.00 0.01 6.58
Low protein biscuits 20 Foods for special diets 212 0.09 0.00 0.02 5.84
Low protein cooking aids 4 Foods for special diets 212 0.02 0.00 0.00 5.57
Salicylic acid 3 Preparations for psoriasis 63 0.05 0.00 0.01 5.40
Acebutolol hydrochloride 8 Beta-adrenoceptor blocking drugs 2,488 0.00 0.00 0.00 5.37
Low protein desserts 6 Foods for special diets 212 0.03 0.00 0.01 5.08
Gluten free/low protein bread 23 Foods for special diets 212 0.11 0.01 0.02 4.92

Prescribing where Castlefields is lower than most

BNF Chemical Chemical Items BNF Subparagraph Subparagraph Items Ratio Mean std Z_Score Plots
Simple 0 Expectorant and demulcent cough preparations 1 0.00 0.96 0.17 -5.69
    Carbocisteine 118 Mucolytics 186 0.63 0.97 0.08 -4.05
    Somatropin 0 Hypothalamic & anterior pituitary hormone & antioestrogens 2 0.00 0.90 0.28 -3.25
      Insulin aspart 102 Short-acting insulins 196 0.52 0.79 0.11 -2.39
      Midazolam hydrochloride 1 Drugs used in status epilepticus 6 0.17 0.80 0.28 -2.23
      Tiotropium bromide 108 Antimuscarinic bronchodilators 327 0.33 0.71 0.18 -2.12
      Letrozole 6 Breast cancer 197 0.03 0.45 0.22 -1.93
      Zinc sulfate monohydrate 0 Zinc 7 0.00 0.74 0.39 -1.90
        Hydralazine hydrochloride 1 Vasodilator antihypertensive drugs 3 0.33 0.85 0.28 -1.85
        Chloramphenicol 37 Antibacterials 60 0.62 0.81 0.11 -1.78