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Prototype Prescribing Outlier Dashboard for Thornley Street Surgery

At OpenPrescribing we are piloting a number of data-driven approaches to identify unusual prescribing and collect feedback on this prescribing to inform development of new tools to support prescribers and organisations to audit and review prescribing. These pilot results are provided for the interest of advanced users, although we don't know how relevant they are in practice. There is substantial variation in prescribing behaviours, across various different areas of medicine. Some variation can be explained by demographic changes, or local policies or guidelines, but much of the remaining variation is less easy to explain.

The DataLab is keen to hear your feedback on the results. You can do this by completing the following survey or emailing us at [email protected]. Please DO NOT INCLUDE IDENTIFIABLE PATIENT information in your feedback. All feedback is helpful, you can send short or detailed feedback.

This report has been developed to automatically identify prescribing patterns at a chemical level which are furthest away from “typical prescribing” and can be classified as an “outlier”. We calculate the number of prescriptions for each chemical in the BNF coding system, the count of all prescriptions within that chemical's BNF subparagraph, for prescriptions dispensed between June 2021 and December 2021. We then calculate the ratio of these counts along with the mean and standard deviation of those ratios across all Practices. From this we can calculate the “z-score”, which is a measure of how many standard deviations a given Practice is from the population mean. We then rank your “z-scores” to find the top 10 results where prescribing is an outlier for prescribing higher than its peers and those where it is an outlier for prescribing lower than its peers.

For each outlier chemical, a kernel density estimation plot of all Practice's chemical:subparagraph ratios is provided, with this Practice's ratio overlaid in red.

It is important to remember that this information was generated automatically and it is therefore likely that some of the behaviour is warranted. This report seeks only to collect information about where this variation may be warranted and where it might not, to inform research on this topic. Our full analytical method code is openly available on GitHub here.

This is a new, experimental feature. We'd love to .

Prescribing where Thornley Street Surgery is higher than most

BNF Chemical Chemical Items BNF Subparagraph Subparagraph Items Ratio Mean std Z_Score Plots
Mianserin hydrochloride 4 Tricyclic and related antidepressant drugs 598 0.01 0.00 0.00 20.44
Famciclovir 4 Herpes simplex and varicella-zoster 17 0.24 0.01 0.02 11.64
Celiprolol hydrochloride 32 Beta-adrenoceptor blocking drugs 1,953 0.02 0.00 0.00 10.69
Perampanel 80 Control of epilepsy 2,387 0.03 0.00 0.00 8.59
Dronabinol/cannabidiol 8 Skeletal muscle relaxants 107 0.07 0.00 0.01 7.97
Domperidone 69 Drugs used in nausea and vertigo 208 0.33 0.05 0.04 6.67
Dutasteride 68 Male sex hormones and antagonists 135 0.50 0.06 0.07 6.27
Hydrocortisone sodium phosphate 7 Use of corticosteroids 275 0.03 0.00 0.00 6.23
Alkyl sulfate 3 Shampoos and some other scalp preparations 75 0.04 0.00 0.01 6.17
Balsalazide sodium 8 Aminosalicylates 36 0.22 0.02 0.03 6.17

Prescribing where Thornley Street Surgery is lower than most

BNF Chemical Chemical Items BNF Subparagraph Subparagraph Items Ratio Mean std Z_Score Plots
Finasteride 32 Male sex hormones and antagonists 135 0.24 0.82 0.11 -5.10
Gliclazide 102 Sulfonylureas 267 0.38 0.93 0.13 -4.05
Permethrin 4 Parasiticidal preparations 54 0.07 0.83 0.24 -3.15
Aciclovir 13 Herpes simplex and varicella-zoster 17 0.76 0.95 0.07 -2.84
Naproxen 104 Non-steroidal anti-inflammatory drugs 245 0.42 0.69 0.10 -2.66
Cabergoline 7 Bromocriptine and other dopaminergic drugs 39 0.18 0.86 0.27 -2.51
Diazepam 85 Anxiolytics 201 0.42 0.75 0.13 -2.48
Gabapentin 152 Control of epilepsy 2,387 0.06 0.24 0.08 -2.15
Loperamide hydrochloride 41 Antimotility drugs 42 0.98 1.00 0.01 -2.01
Fexofenadine hydrochloride 130 Antihistamines 1,155 0.11 0.34 0.12 -1.96