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Prototype Prescribing Outlier Dashboard for Central Surgery

At OpenPrescribing we are piloting a number of data-driven approaches to identify unusual prescribing and collect feedback on this prescribing to inform development of new tools to support prescribers and organisations to audit and review prescribing. These pilot results are provided for the interest of advanced users, although we don't know how relevant they are in practice. There is substantial variation in prescribing behaviours, across various different areas of medicine. Some variation can be explained by demographic changes, or local policies or guidelines, but much of the remaining variation is less easy to explain.

The DataLab is keen to hear your feedback on the results. You can do this by completing the following survey or emailing us at [email protected]. Please DO NOT INCLUDE IDENTIFIABLE PATIENT information in your feedback. All feedback is helpful, you can send short or detailed feedback.

This report has been developed to automatically identify prescribing patterns at a chemical level which are furthest away from “typical prescribing” and can be classified as an “outlier”. We calculate the number of prescriptions for each chemical in the BNF coding system, the count of all prescriptions within that chemical's BNF subparagraph, for prescriptions dispensed between June 2021 and December 2021. We then calculate the ratio of these counts along with the mean and standard deviation of those ratios across all Practices. From this we can calculate the “z-score”, which is a measure of how many standard deviations a given Practice is from the population mean. We then rank your “z-scores” to find the top 10 results where prescribing is an outlier for prescribing higher than its peers and those where it is an outlier for prescribing lower than its peers.

For each outlier chemical, a kernel density estimation plot of all Practice's chemical:subparagraph ratios is provided, with this Practice's ratio overlaid in red.

It is important to remember that this information was generated automatically and it is therefore likely that some of the behaviour is warranted. This report seeks only to collect information about where this variation may be warranted and where it might not, to inform research on this topic. Our full analytical method code is openly available on GitHub here.

This is a new, experimental feature. We'd love to .

Prescribing where Central Surgery is higher than most

BNF Chemical Chemical Items BNF Subparagraph Subparagraph Items Ratio Mean std Z_Score Plots
Darifenacin hydrobromide 304 Drugs for urinary frequency enuresis and incontinence 744 0.41 0.01 0.03 11.43
Amiloride hydrochloride with loop diuretics 14 Potassium sparing diuretics and compounds 15 0.93 0.02 0.08 11.28
Amisulpride 352 Antipsychotic drugs 1,255 0.28 0.03 0.04 6.81
Insulin glulisine 93 Short-acting insulins 261 0.36 0.03 0.05 6.09
Quinapril hydrochloride 12 Angiotensin-converting enzyme inhibitors 3,789 0.00 0.00 0.00 4.58
Acetylcysteine 98 Mucolytics 274 0.36 0.02 0.08 4.23
Estradiol valandestradiol valerate with dienogest 2 Combined hormonal contraceptives 135 0.01 0.00 0.00 4.19
Triptorelin 11 Prostate cancer and gonadorelin analogues 15 0.73 0.09 0.16 4.16
Colestipol hydrochloride 8 Lipid-regulating drugs 6,957 0.00 0.00 0.00 4.15
Sodium chloride 16 Tear deficiency, eye lubricant/astringent 300 0.05 0.00 0.01 4.04

Prescribing where Central Surgery is lower than most

BNF Chemical Chemical Items BNF Subparagraph Subparagraph Items Ratio Mean std Z_Score Plots
Carbocisteine 176 Mucolytics 274 0.64 0.97 0.08 -3.95
Amitriptyline hydrochloride 989 Tricyclic and related antidepressant drugs 1,739 0.57 0.84 0.08 -3.60
Insulin aspart 129 Short-acting insulins 261 0.49 0.79 0.11 -2.62
Co-amilofruse (Amiloride hydrochloride/frusemide) 1 Potassium sparing diuretics and compounds 15 0.07 0.69 0.33 -1.90
Fusidic acid 39 Antibacterial preparations also used systemically 81 0.48 0.75 0.14 -1.88
Co-amoxiclav (Amoxicillin/clavulanic acid) 13 Broad-spectrum penicillins 523 0.02 0.15 0.07 -1.79
Solifenacin 98 Drugs for urinary frequency enuresis and incontinence 744 0.13 0.33 0.11 -1.76
Estradiol 22 Preparations for vaginal/vulval changes 117 0.19 0.55 0.20 -1.74
Tacrolimus 10 Drugs affecting the immune response 21 0.48 0.81 0.19 -1.70
Levetiracetam 104 Control of epilepsy 3,700 0.03 0.09 0.04 -1.70