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Prototype Prescribing Outlier Dashboard for Harden Blakenall

At OpenPrescribing we are piloting a number of data-driven approaches to identify unusual prescribing and collect feedback on this prescribing to inform development of new tools to support prescribers and organisations to audit and review prescribing. These pilot results are provided for the interest of advanced users, although we don't know how relevant they are in practice. There is substantial variation in prescribing behaviours, across various different areas of medicine. Some variation can be explained by demographic changes, or local policies or guidelines, but much of the remaining variation is less easy to explain.

The DataLab is keen to hear your feedback on the results. You can do this by completing the following survey or emailing us at [email protected]. Please DO NOT INCLUDE IDENTIFIABLE PATIENT information in your feedback. All feedback is helpful, you can send short or detailed feedback.

This report has been developed to automatically identify prescribing patterns at a chemical level which are furthest away from “typical prescribing” and can be classified as an “outlier”. We calculate the number of prescriptions for each chemical in the BNF coding system, the count of all prescriptions within that chemical's BNF subparagraph, for prescriptions dispensed between June 2021 and December 2021. We then calculate the ratio of these counts along with the mean and standard deviation of those ratios across all Practices. From this we can calculate the “z-score”, which is a measure of how many standard deviations a given Practice is from the population mean. We then rank your “z-scores” to find the top 10 results where prescribing is an outlier for prescribing higher than its peers and those where it is an outlier for prescribing lower than its peers.

For each outlier chemical, a kernel density estimation plot of all Practice's chemical:subparagraph ratios is provided, with this Practice's ratio overlaid in red.

It is important to remember that this information was generated automatically and it is therefore likely that some of the behaviour is warranted. This report seeks only to collect information about where this variation may be warranted and where it might not, to inform research on this topic. Our full analytical method code is openly available on GitHub here.

This is a new, experimental feature. We'd love to .

Prescribing where Harden Blakenall is higher than most

BNF Chemical Chemical Items BNF Subparagraph Subparagraph Items Ratio Mean std Z_Score Plots
Insulin glargine/lixisenatide 15 Intermediate and long-acting insulins 1,034 0.01 0.00 0.00 10.18
Olmesartan medoxomil/amlodipine 47 Angiotensin-II receptor antagonists 1,572 0.03 0.00 0.00 9.78
Hepatitis B 2 Vaccines and antisera 2 1.00 0.02 0.11 8.52
Tafluprost and timolol 38 Treatment of glaucoma 896 0.04 0.00 0.01 5.01
Ciprofibrate 28 Lipid-regulating drugs 8,745 0.00 0.00 0.00 4.49
Brimonidine tart (Rosacea) 3 Topical preparation for rosacea 3 1.00 0.12 0.22 3.94
Colistimethate sodium 7 Some other antibacterials 7 1.00 0.15 0.25 3.37
Timolol and brimonidine 31 Treatment of glaucoma 896 0.03 0.01 0.01 3.23
Telmisartan with diuretic 22 Angiotensin-II receptor antagonists 1,572 0.01 0.00 0.00 3.19
Sodium chloride 65 Electrolytes and water 74 0.88 0.17 0.24 2.89

Prescribing where Harden Blakenall is lower than most

BNF Chemical Chemical Items BNF Subparagraph Subparagraph Items Ratio Mean std Z_Score Plots
Ivermectin 0 Topical preparation for rosacea 3 0.00 0.88 0.22 -3.94
    Influenza 0 Vaccines and antisera 2 0.00 0.88 0.28 -3.13
      Water for injection 9 Electrolytes and water 74 0.12 0.82 0.25 -2.84
      Allopurinol 351 Gout and cytotoxic induced hyperiuicaemia 447 0.79 0.90 0.05 -2.16
      Codeine phosphate 179 Opioid analgesics 4,525 0.04 0.21 0.11 -1.54
      Lithium carbonate 62 Drugs used for mania and hypomania 334 0.19 0.61 0.28 -1.53
      Finasteride 156 Male sex hormones and antagonists 241 0.65 0.82 0.11 -1.51
      Isosorbide mononitrate 556 Nitrates 987 0.56 0.72 0.11 -1.47
      Estradiol with progestogen 71 Oestrogens and Hormone Replacement Therapy 326 0.22 0.39 0.12 -1.45
      Olanzapine 334 Antipsychotic drugs 3,455 0.10 0.22 0.09 -1.43