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Prototype Prescribing Outlier Dashboard for Joined Up Care Derbyshire STP

At OpenPrescribing we are piloting a number of data-driven approaches to identify unusual prescribing and collect feedback on this prescribing to inform development of new tools to support prescribers and organisations to audit and review prescribing. These pilot results are provided for the interest of advanced users, although we don't know how relevant they are in practice. There is substantial variation in prescribing behaviours, across various different areas of medicine. Some variation can be explained by demographic changes, or local policies or guidelines, but much of the remaining variation is less easy to explain.

The DataLab is keen to hear your feedback on the results. You can do this by completing the following survey or emailing us at [email protected]. Please DO NOT INCLUDE IDENTIFIABLE PATIENT information in your feedback. All feedback is helpful, you can send short or detailed feedback.

This report has been developed to automatically identify prescribing patterns at a chemical level which are furthest away from “typical prescribing” and can be classified as an “outlier”. We calculate the number of prescriptions for each chemical in the BNF coding system, the count of all prescriptions within that chemical's BNF subparagraph, for prescriptions dispensed between June 2021 and December 2021. We then calculate the ratio of these counts along with the mean and standard deviation of those ratios across all STPs. From this we can calculate the “z-score”, which is a measure of how many standard deviations a given STP is from the population mean. We then rank your “z-scores” to find the top 10 results where prescribing is an outlier for prescribing higher than its peers and those where it is an outlier for prescribing lower than its peers.

For each outlier chemical, a kernel density estimation plot of all STP's chemical:subparagraph ratios is provided, with this STP's ratio overlaid in red.

It is important to remember that this information was generated automatically and it is therefore likely that some of the behaviour is warranted. This report seeks only to collect information about where this variation may be warranted and where it might not, to inform research on this topic. Our full analytical method code is openly available on GitHub here.

This is a new, experimental feature. We'd love to .

Prescribing where Joined Up Care Derbyshire STP is higher than most

BNF Chemical Chemical Items BNF Subparagraph Subparagraph Items Ratio Mean std Z_Score Plots
Other topical circulatory preparations 1 Topical circulatory preparations 174 0.01 0.00 0.00 6.22
Lixisenatide 1,736 Other antidiabetic drugs 104,095 0.02 0.00 0.00 5.42
Disulfiram 779 Alcohol dependence 1,313 0.59 0.16 0.10 4.20
Bendroflumethiazide 129,031 Thiazides and related diuretics 146,408 0.88 0.58 0.07 4.04
Methylnaltrexone bromide 4 Peripheral opioid-receptor antagonists 254 0.02 0.00 0.00 3.89
Formoterol fumarate 5,139 Selective beta(2)-agonists 275,680 0.02 0.00 0.00 3.86
Zinc acetate 9 Drugs used in metabolic disorders 11 0.82 0.14 0.18 3.75
Timolol 1,421 Beta-adrenoceptor blocking drugs 428,883 0.00 0.00 0.00 3.74
Benzoyl peroxide 2,376 Topical preparations for acne 13,932 0.17 0.08 0.03 3.65
Lofepramine hydrochloride 4,088 Tricyclic and related antidepressant drugs 230,566 0.02 0.01 0.00 3.60

Prescribing where Joined Up Care Derbyshire STP is lower than most

BNF Chemical Chemical Items BNF Subparagraph Subparagraph Items Ratio Mean std Z_Score Plots
Heparinoid 173 Topical circulatory preparations 174 0.99 1.00 0.00 -6.22
Acamprosate calcium 534 Alcohol dependence 1,313 0.41 0.83 0.10 -4.16
Indapamide 17,071 Thiazides and related diuretics 146,408 0.12 0.41 0.07 -4.04
Iodine compounds 4 Chlorine and iodine 11 0.36 0.93 0.18 -3.16
Prasterone 29 Anabolic steroids 38 0.76 0.97 0.07 -2.94
Cefalexin 5,981 Cephalosporins 6,742 0.89 0.96 0.03 -2.84
Dapagliflozin 4,355 Other antidiabetic drugs 104,095 0.04 0.13 0.03 -2.80
Adapalene and benzoyl peroxide 808 Topical preparations for acne 13,932 0.06 0.17 0.04 -2.66
Co-codamol (Codeine phosphate/paracetamol) 88,725 Non-opioid analgesics and compound preparations 376,488 0.24 0.45 0.08 -2.58
Quinine sulfate 18,779 Antimalarials 23,480 0.80 0.89 0.04 -2.54