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Prototype Prescribing Outlier Dashboard for Buckinghamshire, Oxfordshire And Berkshire West STP

At OpenPrescribing we are piloting a number of data-driven approaches to identify unusual prescribing and collect feedback on this prescribing to inform development of new tools to support prescribers and organisations to audit and review prescribing. These pilot results are provided for the interest of advanced users, although we don't know how relevant they are in practice. There is substantial variation in prescribing behaviours, across various different areas of medicine. Some variation can be explained by demographic changes, or local policies or guidelines, but much of the remaining variation is less easy to explain.

The DataLab is keen to hear your feedback on the results. You can do this by completing the following survey or emailing us at [email protected]. Please DO NOT INCLUDE IDENTIFIABLE PATIENT information in your feedback. All feedback is helpful, you can send short or detailed feedback.

This report has been developed to automatically identify prescribing patterns at a chemical level which are furthest away from “typical prescribing” and can be classified as an “outlier”. We calculate the number of prescriptions for each chemical in the BNF coding system, the count of all prescriptions within that chemical's BNF subparagraph, for prescriptions dispensed between June 2021 and December 2021. We then calculate the ratio of these counts along with the mean and standard deviation of those ratios across all STPs. From this we can calculate the “z-score”, which is a measure of how many standard deviations a given STP is from the population mean. We then rank your “z-scores” to find the top 10 results where prescribing is an outlier for prescribing higher than its peers and those where it is an outlier for prescribing lower than its peers.

For each outlier chemical, a kernel density estimation plot of all STP's chemical:subparagraph ratios is provided, with this STP's ratio overlaid in red.

It is important to remember that this information was generated automatically and it is therefore likely that some of the behaviour is warranted. This report seeks only to collect information about where this variation may be warranted and where it might not, to inform research on this topic. Our full analytical method code is openly available on GitHub here.

This is a new, experimental feature. We'd love to .

Prescribing where Buckinghamshire, Oxfordshire And Berkshire West STP is higher than most

BNF Chemical Chemical Items BNF Subparagraph Subparagraph Items Ratio Mean std Z_Score Plots
Anakinra 4 Rheumatic disease suppressant drugs 76,467 0.00 0.0 0.00 6.33
Phenylephrine hydrochloride and tropicamide 2 Mydriatics and cycloplegics 1,257 0.00 0.0 0.00 6.33
Clozapine 680 Antipsychotic drugs 143,680 0.00 0.0 0.00 6.04
Sacrosidase 3 Drugs used in metabolic disorders 78 0.04 0.0 0.01 5.60
Dequalinium chloride 1 Lozenges and sprays 37 0.03 0.0 0.00 5.60
Fructose 2 Foods for special diets 17,749 0.00 0.0 0.00 5.26
Sultiame 69 Control of epilepsy 402,452 0.00 0.0 0.00 5.22
Atropine sulfate 1 Antimuscarinic drugs 34 0.03 0.0 0.01 4.65
Alprazolam 1 Anxiolytics 67,129 0.00 0.0 0.00 4.30
Macitentan 1 Vasodilator antihypertensive drugs 2,289 0.00 0.0 0.00 3.68

Prescribing where Buckinghamshire, Oxfordshire And Berkshire West STP is lower than most

BNF Chemical Chemical Items BNF Subparagraph Subparagraph Items Ratio Mean std Z_Score Plots
Doxycycline hyclate 36,292 Tetracyclines 65,860 0.55 0.70 0.05 -2.93
Calcipotriol 14,000 Preparations for psoriasis 17,133 0.82 0.87 0.02 -2.62
Levothyroxine sodium 536,120 Thyroid hormones 538,480 1.00 1.00 0.00 -2.39
Amitriptyline hydrochloride 207,438 Tricyclic and related antidepressant drugs 266,959 0.78 0.85 0.03 -2.25
Hydrocortisone 49,469 Topical corticosteroids 171,512 0.29 0.34 0.02 -2.24
Ropinirole hydrochloride 6,087 Dopaminergic drugs used in parkinsonism 68,890 0.09 0.16 0.03 -2.20
Nicotine 784 Nicotine dependence 1,622 0.48 0.73 0.12 -2.01
Alfuzosin hydrochloride 2,521 Drugs for urinary retention 143,709 0.02 0.05 0.02 -2.00
Benzoyl peroxide and clindamycin phosphate 7,566 Topical preparations for acne 26,730 0.28 0.37 0.04 -2.00
Acamprosate calcium 807 Alcohol dependence 1,281 0.63 0.83 0.10 -1.97