Why it matters: Gabapentin and pregabalin are increasingly used in neuropathic and other types of pain, and use is rising rapidly in the NHS. There are also concerns about the potential for abuse and consequently both medicines have been reclassified legally (more information here). There appears to be no robust evidence for dose conversion between gabapentin and pregabalin. We have therefore chosen to use the Defined Daily Dose (DDD) for this measure. This is a similar dose ratio that Toth described in his paper on the substitution of gabapentin with pregabalin.
Please note that this is an experimental measure. We would be grateful for any feedback at [email protected]
Description: Total DDD of pregabalin + gabapentin per 1000 patients
CCGs are ordered by mean percentile over the past six months. Each chart shows the results for the individual CCG, plus deciles across all CCGs in the NHS in England.