Items which should not routinely be prescribed in primary care - oxycodone and naloxone combination product by all Sub-ICB Locations
Why it matters:
Oxycodone and naloxone combination product is used to treat severe pain and can also be used second line in restless legs syndrome. The opioid antagonist naloxone is added to counteract opioid-induced constipation by blocking the action of oxycodone at opioid receptors in the gut.
PrescQIPP CIC has issued a bulletin, which does not identify a benefit of oxycodone and naloxone in a single product over other analgesia (with laxatives if necessary).Due to the significant cost of the oxycodone and naloxone combination product and the unclear role of the combination product in therapy compared with individual products, the joint clinical working group considered oxycodone and naloxone suitable for inclusion in this guidance.
NHS England recommend that GPs:
- Do not initiate.
- Deprescribe in patients currently prescribed this medicine.
- Prescribe only if no other item or intervention is clinically appropriate.
- Prescribe only if no other item or intervention is available.
Description: Cost of oxycodone and naloxone combination per 1000 patients
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Tagged as: Cost Saving, NHS England - items which should not routinely be prescribed in primary care, Opioids, Pain (or browse all measures)
Sub-ICB Locations are ordered by mean percentile over the past six months. Each chart shows the results for the individual Sub-ICB Location, plus deciles across all Sub-ICB Locations in the NHS in England.
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