Items which should not routinely be prescribed in primary care - perindopril arginine by all Sub-ICB Locations
Why it matters:
Perindopril is an ACE inhibitor used in heart failure, hypertension, diabetic nephropathy, and prophylaxis of cardiovascular events. The perindopril arginine salt version is more stable in extremes of climate than the perindopril erbumine salt, which gives it a longer shelf-life. However, perindopril arginine is significantly more expensive than perindopril erbumine and a PrescQIPP CIC review of the topic found no clinical advantage for the arginine salt.
NICE guidance on hypertension in adults recommends that prescribing costs are minimised.
Due to the significant extra costs of the arginine salt and the availability of the erbumine salt, the joint clinical working group considered perindopril arginine suitable for inclusion in this guidance.
NHS England recommend that GPs:
- Do not initiate.
- Deprescribe in patients currently prescribed this medicine.
- Prescribe only if no other item or intervention is clinically appropriate.
- Prescribe only if no other item or intervention is available.
Description: Cost of perindopril arginine per 1000 patients
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Tagged as: Cardiovascular system, Cost Saving, Efficacy, NHS England - items which should not routinely be prescribed in primary care (or browse all measures)
Sub-ICB Locations are ordered by mean percentile over the past six months. Each chart shows the results for the individual Sub-ICB Location, plus deciles across all Sub-ICB Locations in the NHS in England.
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